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High-Yield Obstetrics and Gynaecology for Medical Exams
High-yield O&G revision: antenatal care, pre-eclampsia, bleeding in pregnancy, ectopic, PPH, gestational diabetes, contraception, gynae cancers and exam traps.
Obstetrics and gynaecology is a large share of every licensing exam, and it is full of time-critical decisions. Questions test emergencies (bleeding, hypertension, sepsis), antenatal screening, drugs in pregnancy, contraception and gynaecological cancers. This guide is exam revision based on widely used guidelines.
Key definitions
| Term | Definition |
|---|---|
| Miscarriage | Pregnancy loss before viability (before 24 weeks in UK usage; 20 weeks in US usage) |
| Preterm birth | Before 37 completed weeks |
| Post-term | 42 weeks or more |
| Primary PPH | Blood loss of 500 mL or more within 24 hours of birth |
| Secondary PPH | Abnormal bleeding from 24 hours to 12 weeks after birth |
Antenatal care themes
- Booking: blood group and antibodies, full blood count, screening for infections (HIV, hepatitis B, syphilis), haemoglobinopathy screening, blood pressure, urine.
- Supplements: folic acid before conception and in early pregnancy; a higher dose for higher-risk women (previous neural tube defect, antiepileptic drugs, diabetes, high BMI in some guidelines). Vitamin D per national advice.
- Anomaly and aneuploidy screening: combined first-trimester test (nuchal translucency, hCG, PAPP-A) or later serum testing; cell-free DNA where offered.
- Rhesus-negative women: anti-D prophylaxis and after sensitising events.
- Low-dose aspirin: for women at increased risk of pre-eclampsia, from about 12 weeks.
Hypertension in pregnancy
| Condition | Definition |
|---|---|
| Chronic hypertension | Present before pregnancy or before 20 weeks |
| Gestational hypertension | New hypertension after 20 weeks without proteinuria or other features |
| Pre-eclampsia | New hypertension after 20 weeks with proteinuria or maternal organ dysfunction or uteroplacental dysfunction |
| Eclampsia | Seizures with pre-eclampsia |
| HELLP | Haemolysis, elevated liver enzymes, low platelets |
Management themes
- Antihypertensives: labetalol first line in UK guidance, nifedipine or methyldopa alternatives.
- Magnesium sulfate for severe pre-eclampsia and eclampsia; monitor reflexes, respiratory rate and urine output; calcium gluconate reverses toxicity.
- Definitive treatment is delivery; timing balances maternal and fetal risk.
- Avoid ACE inhibitors and ARBs in pregnancy.
Bleeding in early pregnancy
| Condition | Clues | Key step |
|---|---|---|
| Threatened miscarriage | Bleeding, closed os, viable pregnancy | Reassurance, follow-up |
| Inevitable / incomplete miscarriage | Open os, products of conception | Expectant, medical or surgical management |
| Ectopic pregnancy | Pain, bleeding, positive pregnancy test, empty uterus on transvaginal scan | Methotrexate, surgery or expectant management by criteria; ruptured ectopic needs urgent surgery |
| Molar pregnancy | Very high hCG, hyperemesis, "snowstorm" scan | Evacuation and hCG follow-up |
Trap: any woman of reproductive age with abdominal pain or collapse needs a pregnancy test. Shoulder-tip pain with collapse suggests ruptured ectopic with haemoperitoneum.
Pregnancy of unknown location: serial hCG measurements guide decisions; a rise below the expected amount over 48 hours raises concern for ectopic or failing pregnancy.
Bleeding in late pregnancy
| Feature | Placenta praevia | Placental abruption | Vasa praevia |
|---|---|---|---|
| Bleeding | Painless, bright red | Painful, may be concealed | At membrane rupture |
| Uterus | Soft, non-tender | Tender, hard ("woody") | Normal |
| Fetus | Often stable, malpresentation | Distress common | Rapid fetal distress |
| Key point | No vaginal exam until placental site known | Risk of DIC, shock out of proportion to visible blood | Fetal blood loss, emergency delivery |
Risk factors for abruption: hypertension, smoking, cocaine, trauma, previous abruption.
Postpartum haemorrhage: the four Ts
| Cause | Share | Treatment theme |
|---|---|---|
| Tone (atony) | Most common | Uterine massage, oxytocin, then other uterotonics (ergometrine unless hypertensive, carboprost unless asthmatic, misoprostol), tranexamic acid |
| Trauma | Tears, uterine rupture | Repair |
| Tissue | Retained placenta | Manual removal |
| Thrombin | Coagulopathy | Correct clotting, blood products |
Prevention: active management of the third stage with a uterotonic is recommended for all births by WHO.
Gestational diabetes
Risk factors: high BMI, previous gestational diabetes, previous large baby, family history, certain ethnic backgrounds. Screening is with an oral glucose tolerance test, typically at 24โ28 weeks (earlier if previous gestational diabetes). Management is diet and exercise, then metformin, then insulin per guideline. Postnatally, check glucose because of long-term type 2 diabetes risk.
Labour and delivery
- Stages: first (onset to full dilatation), second (full dilatation to birth), third (birth to delivery of the placenta).
- Cord prolapse: call for help, relieve pressure on the cord (manual elevation, knee-chest or left lateral position), urgent delivery.
- Shoulder dystocia: call for help, McRoberts manoeuvre and suprapubic pressure first, then internal manoeuvres.
- Group B streptococcus: intrapartum antibiotics for colonised women and certain risk factors.
- Fetal heart rate patterns: late decelerations suggest uteroplacental insufficiency.
Drugs in pregnancy (exam favourites)
| Avoid | Safer alternatives commonly cited |
|---|---|
| ACE inhibitors / ARBs | Labetalol, nifedipine, methyldopa |
| Warfarin | Low molecular weight heparin |
| Valproate | Specialist choice of alternative antiepileptic |
| Tetracyclines | Penicillins, cephalosporins |
| Trimethoprim (first trimester) | Nitrofurantoin (avoid near term), cefalexin |
| Isotretinoin, methotrexate | Contraindicated |
| Statins | Stop in pregnancy |
Contraception
| Method | Key points |
|---|---|
| Copper IUD | Most effective emergency contraception; hormone-free |
| Levonorgestrel IUS | Reduces heavy menstrual bleeding |
| Implant | Highly effective, irregular bleeding common |
| Combined pill | Contraindicated with migraine with aura, high VTE risk, smoking over 35, some breast cancer histories; enzyme inducers reduce efficacy |
| Progestogen-only pill | Option when oestrogen is contraindicated |
| Depot injection | Delayed return of fertility, bone density concerns |
WHO medical eligibility criteria rate each method from category 1 (no restriction) to 4 (unacceptable risk) for each condition.
Gynaecology essentials
- Polycystic ovary syndrome: two of three (oligo- or anovulation, hyperandrogenism, polycystic ovaries on ultrasound) after excluding other causes; weight loss, cycle control, letrozole for ovulation induction in many guidelines.
- Endometriosis: cyclical pain, dysmenorrhoea, dyspareunia, subfertility; laparoscopy confirms.
- Ovarian torsion: sudden unilateral pain, vomiting, adnexal mass; urgent surgery.
- Pelvic inflammatory disease: treat empirically; chlamydia and gonorrhoea; Fitz-Hugh-Curtis syndrome.
- Menopause: HRT relieves vasomotor symptoms; women with a uterus need a progestogen with oestrogen.
Gynaecological cancers
| Cancer | Key associations |
|---|---|
| Cervical | Persistent high-risk HPV; prevented by vaccination and screening |
| Endometrial | Postmenopausal bleeding; obesity, unopposed oestrogen, tamoxifen, PCOS, Lynch syndrome |
| Ovarian | Bloating, early satiety; BRCA mutations; CA-125 and ultrasound |
Trap: postmenopausal bleeding needs investigation for endometrial cancer, starting with transvaginal ultrasound for endometrial thickness.
Common exam traps
- Performing a vaginal exam before excluding placenta praevia.
- Forgetting a pregnancy test in a woman with abdominal pain.
- Giving ergometrine to a hypertensive woman or carboprost to an asthmatic.
- Missing magnesium toxicity (loss of reflexes, respiratory depression).
- Forgetting anti-D in a rhesus-negative woman after a sensitising event.
- Prescribing the combined pill to a woman with migraine with aura.
How to revise
O&G rewards algorithm practice: rehearse PPH, eclampsia, cord prolapse and shoulder dystocia drills aloud. MediFlow Exam Prep includes O&G vignettes with explanations. Pair this with high-yield paediatrics.
Summary
- Pre-eclampsia: control blood pressure, magnesium for seizures, deliver.
- PPH: resuscitate and treat the four Ts.
- Early pregnancy bleeding: exclude ectopic.
- Late pregnancy bleeding: placenta praevia before any vaginal exam.
- Know which drugs to avoid and which contraceptives are contraindicated.
Practice questions in MediFlow Exam Prep
Daily questions with explanations, a study plan and mock exams. Start free.
App StoreFrequently asked questions
What is the most tested obstetric emergency?
Postpartum haemorrhage and pre-eclampsia with eclampsia are the most common, followed by ectopic pregnancy, placental abruption, placenta praevia and cord prolapse.
How is postpartum haemorrhage managed in exams?
Call for help and resuscitate, then treat the cause using the four Ts: tone, trauma, tissue and thrombin. Uterine atony is the most common cause; uterotonics and uterine massage come first, with tranexamic acid recommended by WHO.
What drug prevents eclamptic seizures?
Magnesium sulfate is the drug of choice to prevent and treat eclamptic seizures, according to WHO and national guidelines.
Should you do a vaginal examination in antepartum bleeding?
Not before placenta praevia has been excluded by ultrasound, because examination can provoke severe bleeding.
Is this guide clinical advice?
No. It is exam revision material based on widely used guidelines.
Educational content only, not individual medical, legal or immigration advice. Fees, formats and rules change: always confirm with the responsible authority before you apply.
MediFlow Editorial Team
Medical education editors
The MediFlow editorial team researches licensing exams, medical education and healthcare careers worldwide. Every figure is checked against the official exam body, regulator or statistics office and dated; articles are re-reviewed when rules change. MediFlow is operated by ICSL FZE, SPC Free Zone, Sharjah, UAE, with a branch office: Exchange Tower, Business Bay, Dubai.
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