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High-Yield Obstetrics and Gynaecology for Medical Exams

High-yield O&G revision: antenatal care, pre-eclampsia, bleeding in pregnancy, ectopic, PPH, gestational diabetes, contraception, gynae cancers and exam traps.

By MediFlow Editorial TeamLast reviewed: Published: 5 min read

Obstetrics and gynaecology is a large share of every licensing exam, and it is full of time-critical decisions. Questions test emergencies (bleeding, hypertension, sepsis), antenatal screening, drugs in pregnancy, contraception and gynaecological cancers. This guide is exam revision based on widely used guidelines.

Key definitions

TermDefinition
MiscarriagePregnancy loss before viability (before 24 weeks in UK usage; 20 weeks in US usage)
Preterm birthBefore 37 completed weeks
Post-term42 weeks or more
Primary PPHBlood loss of 500 mL or more within 24 hours of birth
Secondary PPHAbnormal bleeding from 24 hours to 12 weeks after birth

Antenatal care themes

  • Booking: blood group and antibodies, full blood count, screening for infections (HIV, hepatitis B, syphilis), haemoglobinopathy screening, blood pressure, urine.
  • Supplements: folic acid before conception and in early pregnancy; a higher dose for higher-risk women (previous neural tube defect, antiepileptic drugs, diabetes, high BMI in some guidelines). Vitamin D per national advice.
  • Anomaly and aneuploidy screening: combined first-trimester test (nuchal translucency, hCG, PAPP-A) or later serum testing; cell-free DNA where offered.
  • Rhesus-negative women: anti-D prophylaxis and after sensitising events.
  • Low-dose aspirin: for women at increased risk of pre-eclampsia, from about 12 weeks.

Hypertension in pregnancy

ConditionDefinition
Chronic hypertensionPresent before pregnancy or before 20 weeks
Gestational hypertensionNew hypertension after 20 weeks without proteinuria or other features
Pre-eclampsiaNew hypertension after 20 weeks with proteinuria or maternal organ dysfunction or uteroplacental dysfunction
EclampsiaSeizures with pre-eclampsia
HELLPHaemolysis, elevated liver enzymes, low platelets

Management themes

  • Antihypertensives: labetalol first line in UK guidance, nifedipine or methyldopa alternatives.
  • Magnesium sulfate for severe pre-eclampsia and eclampsia; monitor reflexes, respiratory rate and urine output; calcium gluconate reverses toxicity.
  • Definitive treatment is delivery; timing balances maternal and fetal risk.
  • Avoid ACE inhibitors and ARBs in pregnancy.

Bleeding in early pregnancy

ConditionCluesKey step
Threatened miscarriageBleeding, closed os, viable pregnancyReassurance, follow-up
Inevitable / incomplete miscarriageOpen os, products of conceptionExpectant, medical or surgical management
Ectopic pregnancyPain, bleeding, positive pregnancy test, empty uterus on transvaginal scanMethotrexate, surgery or expectant management by criteria; ruptured ectopic needs urgent surgery
Molar pregnancyVery high hCG, hyperemesis, "snowstorm" scanEvacuation and hCG follow-up

Trap: any woman of reproductive age with abdominal pain or collapse needs a pregnancy test. Shoulder-tip pain with collapse suggests ruptured ectopic with haemoperitoneum.

Pregnancy of unknown location: serial hCG measurements guide decisions; a rise below the expected amount over 48 hours raises concern for ectopic or failing pregnancy.

Bleeding in late pregnancy

FeaturePlacenta praeviaPlacental abruptionVasa praevia
BleedingPainless, bright redPainful, may be concealedAt membrane rupture
UterusSoft, non-tenderTender, hard ("woody")Normal
FetusOften stable, malpresentationDistress commonRapid fetal distress
Key pointNo vaginal exam until placental site knownRisk of DIC, shock out of proportion to visible bloodFetal blood loss, emergency delivery

Risk factors for abruption: hypertension, smoking, cocaine, trauma, previous abruption.

Postpartum haemorrhage: the four Ts

CauseShareTreatment theme
Tone (atony)Most commonUterine massage, oxytocin, then other uterotonics (ergometrine unless hypertensive, carboprost unless asthmatic, misoprostol), tranexamic acid
TraumaTears, uterine ruptureRepair
TissueRetained placentaManual removal
ThrombinCoagulopathyCorrect clotting, blood products

Prevention: active management of the third stage with a uterotonic is recommended for all births by WHO.

Gestational diabetes

Risk factors: high BMI, previous gestational diabetes, previous large baby, family history, certain ethnic backgrounds. Screening is with an oral glucose tolerance test, typically at 24โ€“28 weeks (earlier if previous gestational diabetes). Management is diet and exercise, then metformin, then insulin per guideline. Postnatally, check glucose because of long-term type 2 diabetes risk.

Labour and delivery

  • Stages: first (onset to full dilatation), second (full dilatation to birth), third (birth to delivery of the placenta).
  • Cord prolapse: call for help, relieve pressure on the cord (manual elevation, knee-chest or left lateral position), urgent delivery.
  • Shoulder dystocia: call for help, McRoberts manoeuvre and suprapubic pressure first, then internal manoeuvres.
  • Group B streptococcus: intrapartum antibiotics for colonised women and certain risk factors.
  • Fetal heart rate patterns: late decelerations suggest uteroplacental insufficiency.

Drugs in pregnancy (exam favourites)

AvoidSafer alternatives commonly cited
ACE inhibitors / ARBsLabetalol, nifedipine, methyldopa
WarfarinLow molecular weight heparin
ValproateSpecialist choice of alternative antiepileptic
TetracyclinesPenicillins, cephalosporins
Trimethoprim (first trimester)Nitrofurantoin (avoid near term), cefalexin
Isotretinoin, methotrexateContraindicated
StatinsStop in pregnancy

Contraception

MethodKey points
Copper IUDMost effective emergency contraception; hormone-free
Levonorgestrel IUSReduces heavy menstrual bleeding
ImplantHighly effective, irregular bleeding common
Combined pillContraindicated with migraine with aura, high VTE risk, smoking over 35, some breast cancer histories; enzyme inducers reduce efficacy
Progestogen-only pillOption when oestrogen is contraindicated
Depot injectionDelayed return of fertility, bone density concerns

WHO medical eligibility criteria rate each method from category 1 (no restriction) to 4 (unacceptable risk) for each condition.

Gynaecology essentials

  • Polycystic ovary syndrome: two of three (oligo- or anovulation, hyperandrogenism, polycystic ovaries on ultrasound) after excluding other causes; weight loss, cycle control, letrozole for ovulation induction in many guidelines.
  • Endometriosis: cyclical pain, dysmenorrhoea, dyspareunia, subfertility; laparoscopy confirms.
  • Ovarian torsion: sudden unilateral pain, vomiting, adnexal mass; urgent surgery.
  • Pelvic inflammatory disease: treat empirically; chlamydia and gonorrhoea; Fitz-Hugh-Curtis syndrome.
  • Menopause: HRT relieves vasomotor symptoms; women with a uterus need a progestogen with oestrogen.

Gynaecological cancers

CancerKey associations
CervicalPersistent high-risk HPV; prevented by vaccination and screening
EndometrialPostmenopausal bleeding; obesity, unopposed oestrogen, tamoxifen, PCOS, Lynch syndrome
OvarianBloating, early satiety; BRCA mutations; CA-125 and ultrasound

Trap: postmenopausal bleeding needs investigation for endometrial cancer, starting with transvaginal ultrasound for endometrial thickness.

Common exam traps

  • Performing a vaginal exam before excluding placenta praevia.
  • Forgetting a pregnancy test in a woman with abdominal pain.
  • Giving ergometrine to a hypertensive woman or carboprost to an asthmatic.
  • Missing magnesium toxicity (loss of reflexes, respiratory depression).
  • Forgetting anti-D in a rhesus-negative woman after a sensitising event.
  • Prescribing the combined pill to a woman with migraine with aura.

How to revise

O&G rewards algorithm practice: rehearse PPH, eclampsia, cord prolapse and shoulder dystocia drills aloud. MediFlow Exam Prep includes O&G vignettes with explanations. Pair this with high-yield paediatrics.

Summary

  • Pre-eclampsia: control blood pressure, magnesium for seizures, deliver.
  • PPH: resuscitate and treat the four Ts.
  • Early pregnancy bleeding: exclude ectopic.
  • Late pregnancy bleeding: placenta praevia before any vaginal exam.
  • Know which drugs to avoid and which contraceptives are contraindicated.

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Frequently asked questions

What is the most tested obstetric emergency?

Postpartum haemorrhage and pre-eclampsia with eclampsia are the most common, followed by ectopic pregnancy, placental abruption, placenta praevia and cord prolapse.

How is postpartum haemorrhage managed in exams?

Call for help and resuscitate, then treat the cause using the four Ts: tone, trauma, tissue and thrombin. Uterine atony is the most common cause; uterotonics and uterine massage come first, with tranexamic acid recommended by WHO.

What drug prevents eclamptic seizures?

Magnesium sulfate is the drug of choice to prevent and treat eclamptic seizures, according to WHO and national guidelines.

Should you do a vaginal examination in antepartum bleeding?

Not before placenta praevia has been excluded by ultrasound, because examination can provoke severe bleeding.

Is this guide clinical advice?

No. It is exam revision material based on widely used guidelines.

Educational content only, not individual medical, legal or immigration advice. Fees, formats and rules change: always confirm with the responsible authority before you apply.

MediFlow Editorial Team

Medical education editors

The MediFlow editorial team researches licensing exams, medical education and healthcare careers worldwide. Every figure is checked against the official exam body, regulator or statistics office and dated; articles are re-reviewed when rules change. MediFlow is operated by ICSL FZE, SPC Free Zone, Sharjah, UAE, with a branch office: Exchange Tower, Business Bay, Dubai.

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